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Updated: Jun 4, 2025

An All-in-one Sample Holder for Macromolecular X-ray Crystallography with Minimal Background Scattering
Published on: July 6, 2019
A fully contained sample holder capable of electron-yield detection at soft X-ray energies
S Olivia Gunther1, Patrick W Smith1, Jacob A Branson1
1Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Abstract:
A holder has been developed that enables electron yield-detected soft X-ray spectroscopy of fully contained samples at low temperature. Crucially, this design uses elements of the sample containment to collect ejected electrons, removing the need to expose samples directly to the vacuum environment of the spectrometer. The design is modular and should be adaptable to a number of different endstation configurations, enabling spectroscopy of air-sensitive, radioactive and vacuum-sensitive (biological) samples.
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