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Updated: Jun 4, 2025

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
Published on: January 17, 2020
Two-dimensional metal-organic frameworks (2D-MOFs) as a carrier for enzyme immobilization: A review on design and
Pravin D Patil1, Niharika Gargate2, Manishkumar S Tiwari3
1Department of Basic Science & Humanities, Mukesh Patel School of Technology Management & Engineering, SVKM's Narsee Monjee Institute of Management Studies (NMIMS) Deemed-to-University, Mumbai 400056, India.
Abstract:
In the realm of carriers for enzyme immobilization, the use of MOFs has accelerated owing to their exceptional porosity and stability. Among these, 2D metal-organic frameworks (2D-MOFs) have emerged as promising supports for enzyme immobilization. This review highlights advancements in their synthesis, structural properties, and functional characteristics, focusing on enhancing catalytic performance and stability. Brief insights into computational approaches for optimizing these nanostructures and their catalytic efficiency are provided. The unique synergy between 2D MOF-based nanozymes and enzymes is discussed, showcasing their potential in diverse applications. Challenges in their practical implementation, prospective solutions, and future research directions are also outlined. This review emphasizes the transformative potential of 2D MOFs, focusing on their design and bioapplications and paving the way for innovative and sustainable strategies.

