Prevalence of comorbidities and cardiovascular risk factor management in hand osteoarthritis: a cross-sectional study
Sylvain Mathieu1,2, Françoise Fayet3, Marie-Hélène Salembien3
1Rheumatology Department, Gabriel Montpied Teaching Hospital, Université Clermont Auvergne, CHU Clermont-Ferrand, INSERM, Neuro-Dol, Place H. Dunant, Clermont-Ferrand, Clermont-Ferrand, 63000, France. smathieu@chu-clermontferrand.fr.
Insights
Hand osteoarthritis patients show increased cardiovascular risk, particularly those with uncontrolled LDL cholesterol. This highlights the need for proactive assessment and management of cardiovascular risk factors in this population.
Area of Science:
- Rheumatology
- Cardiology
- Public Health
Background:
- Hand osteoarthritis (HOA) is a prevalent condition affecting quality of life.
- Comorbidities and cardiovascular (CV) risk factors are common in HOA patients.
- Current management guidelines for CV risk factors in HOA are not well-established.
Purpose of the Study:
- To determine the prevalence of comorbidities in HOA patients.
- To assess the management of CV risk factors according to guidelines.
- To evaluate the association between HOA and CV risk.
Main Methods:
- A cross-sectional study included 110 HOA patients.
- Clinical parameters and CV risk factors (blood pressure, BMI, dyslipidemia) were assessed.
- CV risk was calculated using SCORE2 or SCORE2-OP algorithms.
Main Results:
- Twenty-eight patients had comorbidities, often associated with older age, male sex, and lower quality of life.
- Median SCORE2 was 5.1%, negatively correlated with grip strength.
- 82.5% of patients with intermediate/high CV risk had uncontrolled LDL cholesterol levels.
Conclusions:
- HOA patients exhibit an increased CV risk, linked to suboptimal LDL cholesterol management.
- HOA patients present a pro-atherogenic profile.
- Routine assessment and guideline-based management of CV risk factors are crucial for HOA patients.
Objectives:
To assess the prevalence of comorbidities and management of cardiovascular risk factors according to established guidelines for patients with hand osteoarthritis.
Methods:
A cross-sectional study was conducted that included 110 hand osteoarthritis patients. The clinical parameters (pain, function, grip strength, quality of life, sarcopenia, and comorbidities) were assessed along with cardiovascular (CV) risk factors (blood pressure, body mass index, and dyslipidaemia). CV risk was assessed using SCORE2 or SCORE2-OP algorithms. Comparisons of patient characteristics were performed using Student's or chi-squared tests.
Results:
Twenty-eight patients were identified with comorbidities, and they tended to be older, male, and with a lower quality of life. The median SCORE2 was 5.1%. SCORE2 was negatively associated with grip strength (r=-0.27, p = 0.02). There was no difference in SCORE2 between hand osteoarthritis patients with (n = 60) and without (n = 50) neuropathic-like pain (5.6 ± 3.7 versus 6.2 ± 3.3%; p = 0.38). Among the 40 patients with an intermediate or high CV risk, 33 (82.5%) were off target for low-density lipoproteins (LDL) level with no lipid-lowering treatment (n = 29) or an insufficient statin treatment (n = 4). Obesity was observed in 24 patients (21.8%) and 30 (27.3%) were overweight. Forty-two patients (41.2%) had blood hypertension (41 systolic and one diastolic patient) despite treatment for 9 patients.
Conclusions:
We found an increased CV risk in hand osteoarthritis patients who had an insufficient LDL cholesterol target achievement. Hand osteoarthritis patients appear to have a pro-atherogenic profile. These results suggest that CV risk factors should be assessed in patients with hand osteoarthritis and managed according to recommended guidelines.
Related Concept Videos
01:29Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
01:20COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
01:26COPD: Management Using Bronchodilators and Corticosteroids
01:22Mitral Valve Prolapse II: Assessment and Management
01:23Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD: