Post-transcriptional regulation of behavior plasticity in social insects

Social insects often show remarkable behavioral plasticity, which is closely associated with their respective castes. The underpinnings of this plasticity are complex, involving genetic differences among individuals within a colony and regulation of gene expression at multiple levels. Post-transcriptional regulation, which increases the complexity of the transcriptome, plays a crucial role in the multilayer regulatory network that influences social insect behavior. We provide an overview of the impact of three post-transcriptional regulatory processes on the reproductive division of labor and worker division of labor in social insects: alternative splicing, RNA modifications, and noncoding RNAs. We also discuss the relationship between post-transcriptional regulation and chromatin modification.