Related Experiment Video
Updated: Jun 4, 2025

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
Published on: January 5, 2018
Serious harm reduction protective behavioral strategies reduce consequences associated with alcohol-induced blackouts
Veronica L Richards1, Robert J Turrisi2, Shannon D Glenn2
1TSET Health Promotion Research Center, University of Oklahoma Health Sciences Center, Tulsa, OK, USA; Department of Health Promotion Sciences, University of Oklahoma Health Sciences Center, Tulsa, OK, USA.
Objective:
Alcohol-induced blackouts (AIBs) have been associated with increased alcohol-related consequences. Serious harm reduction (SHR) protective behavioral strategies may reduce consequences when students are drinking heavily. We examined whether SHR weakened the relationship between AIBs and a) total consequences and b) serious consequences (e.g., sexual assault) only.
Methods:
Students were eligible if they were aged 18-22 years, in their second or third year of college, reported drinking 4 + drinks on a typical Friday or Saturday, experienced ≥ 1 AIB in the past semester, owned an iPhone, and were willing to wear a sensor for 3 days each weekend. Students (N = 79, 55.7 % female, 86.1 % White, Mage = 20.1) wore sensors and completed daily diaries over four consecutive weekends (852 total surveys; 89.9 % completion rate). Linear multilevel models were conducted to test for moderating effects of SHR.
Results:
SHR weakened the association between AIBs and total consequences. At low (-1 SD) SHR, days with an AIB had an additional 1.46 consequences compared to days without an AIB, on average. At high (+1 SD) SHR, days with an AIB had an additional 0.94 consequences compared to days without an AIB, on average. SHR did not change the association between AIBs and serious consequences.
Conclusions:
Students experienced approximately 50% more consequences on nights when they had an AIB and used below average numbers of SHR compared to nights when they had an AIB and used above average numbers of SHR. These findings suggest that student drinking interventions should include SHR to reduce harm associated with drinking and AIBs.
More Related Videos
05:40The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
Published on: April 28, 2022
07:31Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
Published on: January 7, 2019
Related Concept Videos
CNS Depressants: Alcohol and Nicotine
Depressants
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...
Self-Presentation: Self-Monitoring and Self-Handicapping
CNS Depressants: Barbiturates and Benzodiazepines
Alcohols from Carbonyl Compounds: Reduction
Catalytic hydrogenation is similar to the reduction of an alkene or alkyne by adding H2 across the pi bond in the presence of transition metal catalysts like Raney Ni, Pd–C, Pt, or Ru. Aldehydes and ketones can be reduced by this method, often under mild to moderate heat (25–100°C) and...