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Radical Autoxidation

Radical Autoxidation

The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...

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Preparation and Reactions of Sulfides

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Antidotes

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Antidotes are medicinal substances used to counteract the harmful effects of toxins or drugs in the body. They function in various ways, each uniquely designed to combat specific toxic compounds.
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Related Experiment Video

Updated: Jun 4, 2025

Use of Electron Paramagnetic Resonance in Biological Samples at Ambient Temperature and 77 K

Use of Electron Paramagnetic Resonance in Biological Samples at Ambient Temperature and 77 K

Published on: January 11, 2019

Organoselenium compounds beyond antioxidants.

Ritu Mamgain¹, Garima Mishra², Saumya Kriti¹

¹Chemistry Division, School of Advanced Sciences (SAS), Vellore Institute of Technology - Chennai, Chennai, India.

Future Medicinal Chemistry

|December 23, 2024

Summary

Organoselenium compounds are synthesized for diverse medicinal applications beyond their antioxidant roles. This review highlights their anticancer, antimicrobial, and anti-inflammatory uses over the last decade.

Keywords:

Antidiabetic Organoselenium compounds anti-Alzheimer’s anti-cancer antimicrobial antithyroids antiviral

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Area of Science:

Medicinal Chemistry
Organic Chemistry
Pharmacology

Background:

Organoselenium chemistry is crucial for developing biologically active compounds.
Early research focused on antioxidant properties of organoselenium compounds.
Recent advancements emphasize diverse therapeutic applications.

Purpose of the Study:

To review the synthesis of organoselenium compounds.
To explore their medicinal applications in various therapies.
To provide a resource for medicinal chemists.

Main Methods:

Literature review of organoselenium compound synthesis.
Analysis of studies on therapeutic applications.
Focus on research from the past 10 years.

Main Results:

Organoselenium compounds show promise in anticancer therapies.
Antimicrobial, antiviral, antidiabetic, and anti-inflammatory activities are documented.
Synthesis strategies have evolved to target specific biological properties.

Conclusions:

Organoselenium compounds offer a broad spectrum of therapeutic potential.
Continued research is vital for drug development in this field.
This review serves as a comprehensive guide to recent advancements.