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HLA-DRB1*14:270 and -DPA1*01:222 Identified by Next-Generation Sequencing in Russian Bone Marrow Donors

Evgeny Leonov1, Ekaterina Khamaganova1, Elena Kuzminova1

  • 1National Medical Research Center for Hematology, Moscow, Russia.

HLA
|December 23, 2024
PubMed

Keywords:
HLA‐DPA1HLA‐DRB1new allelenext‐generation sequencing

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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