Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Malignant melanoma and pregnancy.

D S Reintgen, K S McCarty, R Vollmer

    Cancer
    |March 15, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Erysipelothrix rhusiopathiae occurrence, epidemiology and vaccine reactions in cetaceans: a thirty-year retrospective based on two global surveys.

    Diseases of aquatic organisms·2025
    Same author

    Supplementation of a new combination of prebiotic and postbiotic shapes fecal microbiota of old dogs while influencing immune parameters.

    Scientific reports·2025
    Same author

    Radiographer educational requirements for adaptive radiotherapy techniques: A mixed-methods regional scoping study.

    Radiography (London, England : 1995)·2025
    Same author

    That Barbaric "Key".

    The Dental register·2021
    Same author

    Particulate matter and airborne endotoxin concentration in calf barns and their association with lung consolidation, inflammation, and infection.

    Journal of dairy science·2021
    Same author

    Occurrence of 'gang of five' Shiga toxin-producing Escherichia coli serogroups on Belgian dairy cattle farms by overshoe sampling.

    Letters in applied microbiology·2020

    Melanoma developing during pregnancy may have a worse prognosis, but subsequent pregnancies do not impact recurrence or survival rates for women diagnosed with cutaneous melanoma.

    Area of Science:

    • Oncology
    • Dermatology
    • Reproductive Medicine

    Background:

    • Pregnancy's impact on malignant melanoma prognosis remains unclear.
    • Stage I cutaneous melanoma in women of childbearing age requires further investigation regarding pregnancy influences.

    Purpose of the Study:

    • To evaluate the influence of pregnancy on survival and recurrence in patients with Stage I cutaneous melanoma.
    • To compare outcomes for melanoma diagnosed during pregnancy versus subsequent pregnancies.

    Main Methods:

    • Retrospective computer-aided study of 101 women with Stage I cutaneous melanoma at Duke University Comprehensive Cancer Center.
    • Comparison of patients with melanoma during pregnancy (Group 1) and those pregnant within 5 years of diagnosis (Group 2) against matched control groups.
    • Actuarial survival and disease-free interval analysis using multivariate regression.

    Related Experiment Videos

    Main Results:

    • No significant difference in survival was observed between pregnant patients and controls.
    • Melanoma diagnosed during pregnancy showed a significantly worse disease-free interval (P=0.04), which remained apparent after multivariate analysis (P=0.02).
    • Subsequent pregnancies did not affect disease-free interval or survival (P=0.31).

    Conclusions:

    • While melanoma occurring during pregnancy may present a worse prognosis, it does not affect overall survival.
    • Subsequent pregnancies after a cutaneous melanoma diagnosis do not influence recurrence rates or survival.