Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

305
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
305
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

296
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
296
Applications of IR Spectroscopy: Overview01:11

Applications of IR Spectroscopy: Overview

482
The non-destructive nature and ability to provide valuable chemical information make IR spectroscopy a versatile technique with broad applications in various scientific and industrial fields. IR spectroscopy is commonly used to identify and characterize organic and inorganic compounds. It provides information about the functional groups present in a molecule and the bonding between atoms. This helps in the structural elucidation of compounds during organic synthesis, pharmaceutical research,...
482
Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview01:13

Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview

284
Attenuated total reflectance (ATR) infrared spectroscopy is a powerful analytical technique used to study the composition of materials. It is widely employed in chemistry, materials science, forensic science, and other fields where sample characterization is required. ATR has several advantages over traditional transmission IR spectroscopy, including the requirement of little to no sample preparation and the ability to analyze a wide range of samples.
The ATR process begins by directing a beam...
284

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Infrared Spectroelectrochemical Insights into Rhenium-Based Supramolecular Assemblies for Electron Storage and Transfer.

Inorganic chemistry·2026
Same author

Plasmonic Nanocavity-Induced Degradation Pathway of Boronic Acid Biosensing Interfaces Revealed by <i>In Situ</i> Tip-Enhanced Raman Spectroscopy.

ACS nano·2026
Same author

Noninvasive Analysis of Skin Emanations during Cupping Therapy by Thin-Film Solid-Phase Microextraction and Dielectric Barrier Discharge Ionization Mass Spectrometry.

Analytical chemistry·2026
Same author

Surface-Enhanced Raman Spectroscopy: A Game Changer for Metabolomics Research.

Nano letters·2026
Same author

Hydrogen-Bond Network-Activated O<sub>2</sub> in ChCl-Based Deep Eutectic Solvent Lowers the Overpotential of Oxygen Reduction Reaction on Carbon Electrode.

ChemSusChem·2026
Same author

Interstitial C/N Doping Stabilizes Pd@Pt Core-Shell Electrocatalysts by Atomic-Scale Interfacial Anchoring and Metal Dissolution Suppression.

Angewandte Chemie (International ed. in English)·2026
Same journal

Direct impure water electrolysis at industrial scale.

Chemical Society reviews·2026
Same journal

Catalytic valorization of polyolefins: from catalysts and processes to reactors.

Chemical Society reviews·2026
Same journal

Designing stable π-radicals.

Chemical Society reviews·2026
Same journal

Antibacterial drug discovery: challenges and preclinical promises from synthetic small molecules.

Chemical Society reviews·2026
Same journal

Selective carbon-carbon bond cleavage involving alkene moieties.

Chemical Society reviews·2026
Same journal

Circularly polarized luminescence: an easy path from molecules to supramolecular systems and beyond.

Chemical Society reviews·2026
See all related articles
  1. Home
  2. Surface-enhanced Raman Spectroscopy: A Half-century Historical Perspective.
  1. Home
  2. Surface-enhanced Raman Spectroscopy: A Half-century Historical Perspective.

Related Experiment Video

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
09:46

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging

Published on: April 28, 2022

3.8K

Surface-enhanced Raman spectroscopy: a half-century historical perspective.

Jun Yi1, En-Ming You2, Ren Hu1

  • 1State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, School of Electronic Science and Engineering, College of Environment and Ecology, State Key Laboratory of Marine Environmental Science, Department of Physics, iChEM, IKKEM, Xiamen University, Xiamen 361005, China. zqtian@xmu.edu.cn.

Chemical Society Reviews
|December 23, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

Surface-enhanced Raman spectroscopy (SERS) has advanced over 50 years, driven by innovations in nanoscience and plasmonics. This review details SERS

More Related Videos

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

3.9K
Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.2K

Related Experiment Videos

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
09:46

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging

Published on: April 28, 2022

3.8K
Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

3.9K
Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.2K

Area of Science:

  • Analytical Chemistry
  • Spectroscopy
  • Nanoscience
  • Plasmonics

Background:

  • Surface-enhanced Raman spectroscopy (SERS) has a rich 50-year history.
  • Its development is intertwined with advances in nanoscience and plasmonics.
  • Key pioneers have made significant contributions to its evolution.

Purpose of the Study:

  • To provide a comprehensive history and theoretical foundations of SERS.
  • To classify the progression of SERS methodologies into four pivotal phases.
  • To highlight the trajectory of SERS and related techniques like TERS and SHINERS.
  • To emphasize innovative methods for overcoming developmental bottlenecks and expanding SERS applications.
  • To extract inspirational lessons from the pioneers of SERS research.

Main Methods:

  • Historical review of SERS discovery and development.
  • Classification of SERS evolution into four distinct phases.
  • Analysis of SERS, TERS, and SHINERS trajectories.
  • Emphasis on innovative methodologies and their impact.
  • Extraction of key principles from pioneer contributions.

Main Results:

  • SERS has progressed through distinct developmental phases, from initial discovery to a recent boom.
  • Innovations in nanoscience and plasmonics have been crucial for SERS advancement.
  • Overcoming bottlenecks has expanded the versatility and applications of SERS.
  • Related techniques like TERS and SHINERS have emerged, broadening the scope of Raman spectroscopy.
  • Lessons learned from pioneers emphasize embracing new technologies and interdisciplinary collaboration.

Conclusions:

  • SERS is a powerful analytical technique with a dynamic 50-year history.
  • Continuous innovation and interdisciplinary collaboration are vital for scientific advancement.
  • The journey of SERS offers valuable insights into scientific discovery and perseverance.
  • Future directions in SERS will likely involve further integration with emerging technologies.
  • The spirit of innovation demonstrated by SERS pioneers serves as a model for future research.