[Impact of tumor size on actuarial survival of patients with primary breast sarcoma: a case-control study]

O determine whether tumor size, categorized as >5 cm or ≤5 cm, influences overall survival in patients with primary breast sarcoma.

The study population consisted of patients diagnosed with primary breast sarcoma between January 1, 2010, and December 31, 2020. Patients with histologically confirmed primary breast sarcoma were included and divided into two groups according to tumor size: cases (>5 cm) and controls (≤5 cm). Survival was evaluated throughout the follow-up period ranging from 2 years and 6 months to 3 years and 6 months.

Of 2173 breast cancer cases registered during the study period, 20 patients met the inclusion criteria for primary breast sarcoma. Of these, 13 ones had tumors >5 cm, while 7 ones had tumors ≤5 cm. Mean age of patients was 48 years, 70% of patients were older 40 years. Tumors larger than 5 cm represented 65% of cases. However, no significant difference in overall survival was observed between both groups (p=0.37).

Although a difference in median survival was found between patients with tumors larger and smaller than 5 cm, multivariate analysis did not demonstrate tumors > 5 cm as a significant prognostic factor for decreased survival.