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Saving a hopeless tooth with a four-wall bone defect: A case report.
Takayoshi Nagahara1,2, Tomoyuki Iwata2, Keinoshin Wada3
1Department of Dental, Nippon Kokan Fukuyama Hospital, Fukuyama, Japan.
Clinical Advances in Periodontics
|December 24, 2024
Summary
Recombinant human fibroblast growth factor-2 (rhFGF-2) combined with beta-tricalcium phosphate (β-TCP) shows promise for treating four-wall periodontal bone defects. This combination therapy aids in periodontal regeneration and tooth preservation.
Area of Science:
- Periodontal Medicine
- Regenerative Dentistry
- Biomaterials Science
Background:
- Recombinant human fibroblast growth factor-2 (rhFGF-2) promotes periodontal tissue regeneration.
- rhFGF-2 combined with bone substitutes enhances clinical and radiographic outcomes in periodontal defects.
- Four-wall bone defects present a significant challenge in periodontal therapy.

