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Image-guided percutaneous mesenteric biopsy: diagnostic yield and safety profile
Sarah M Daggett1, Perry J Pickhardt1, Matthew Elissa1
1University of Wisconsin School of Medicine and Public Health, Madison, USA.
Abdominal Radiology (New York)
|December 27, 2024
Summary
Image-guided percutaneous biopsy of mesenteric lesions demonstrates a high diagnostic yield (96.4%) and a favorable safety profile. Ultrasound guidance significantly reduces skin-to-target distance and can create safer biopsy paths.
Area of Science:
- Radiology
- Interventional Radiology
- Gastroenterology
Background:
- Percutaneous image-guided biopsy is crucial for diagnosing mesenteric lesions.
- Evaluating the efficacy and safety of this procedure is essential for patient management.
Purpose of the Study:
- To assess the diagnostic yield and safety of percutaneous image-guided biopsy for mesenteric lesions.
- To compare different biopsy techniques and imaging modalities.
Main Methods:
- Retrospective review of 195 percutaneous mesenteric biopsies performed between 2000 and 2022.
- Data collection included patient demographics, procedural details (imaging guidance, biopsy type), and pathology results.
- Analysis of diagnostic yield, concordance with final diagnosis, and complication rates.
Main Results:
- The overall diagnostic yield was high at 96.4%, with core needle biopsy achieving 97.7% and fine-needle aspiration (FNA) achieving 80.6%.
- Ultrasound guidance was used in 89% of cases and reduced skin-to-target distance by 35% compared to CT.
- Complications occurred in 5.6% of biopsies and were all minor.
Conclusions:
- Image-guided percutaneous biopsy, particularly core needle biopsy under ultrasound guidance, is a safe and highly effective method for diagnosing mesenteric lesions.
- Ultrasound offers advantages in reducing target depth and creating safe biopsy corridors.
- This technique provides a favorable safety profile and high diagnostic accuracy for tissue diagnosis.

