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Budd-Chiari Syndrome: Update on Classification and Intravascular US
Anne Sailer1, Nariman Nezami2, Parham Tabeli Bouroujeni3
1Section of Interventional Radiology, Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar St, PO Box 208042, Room TE-2, New Haven, CT 06520.
Budd-Chiari syndrome (BCS) is caused by hepatic venous outflow obstruction. Understanding the BCS classification system and using intravascular ultrasound (IVUS) aids in guiding effective interventional therapies for BCS.
Area of Science:
- Interventional Radiology
- Hepatology
- Vascular Medicine
Background:
- Budd-Chiari syndrome (BCS) arises from hepatic venous outflow obstruction, leading to sinusoidal congestion, portal hypertension, and potential cirrhosis.
- Obstruction can affect hepatic veins (HVs) or the inferior vena cava (IVC), presenting globally or segmentally.
- Effective treatment necessitates a thorough understanding of causal factors, lesion characteristics, clinical status, and liver function.
Purpose of the Study:
- To highlight the importance of the Budd-Chiari syndrome (BCS) classification system in guiding interventional therapy.
- To underscore the utility of intravascular ultrasound (IVUS) in characterizing BCS lesions and aiding treatment decisions.
- To emphasize the role of radiologists in understanding the BCS classification for optimal patient management.
Main Methods:
- Review and application of the established Budd-Chiari syndrome (BCS) classification system.
- Utilization of intravascular ultrasound (IVUS) for detailed lesion characterization and procedural guidance.
- Analysis of treatment strategies including angioplasty, stent placement, and portosystemic shunt creation.
Main Results:
- The BCS classification system provides a framework for standardizing diagnosis and interventional therapy.
- IVUS aids in BCS lesion characterization, guiding decisions on stent placement and portosystemic shunt creation.
- IVUS can improve procedural efficiency and success rates while reducing radiation and contrast agent use.
Conclusions:
- A comprehensive understanding of the BCS classification system is essential for radiologists.
- Intravascular ultrasound (IVUS) is a valuable tool for characterizing BCS lesions and optimizing interventional procedures.
- Integrating the BCS classification with IVUS facilitates tailored and effective treatment strategies for Budd-Chiari syndrome.
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