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Updated: Jun 4, 2025

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering
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Long-acting injectable in situ forming implants: Impact of polymer attributes and API

Xiaoyi Wang1, Ruifeng Wang2, Mckenzie Roy2

  • 1Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA; State Key Laboratory of Biochemical Engineering, Key Laboratory of Biopharmaceutical Preparation and Delivery (CAS), Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, PR China(1).

International Journal of Pharmaceutics
|December 28, 2024
PubMed
Summary

This study reveals that Poly(DL-lactide-co-glycolide) (PLGA) properties significantly influence drug release from in situ forming implants. The interplay between drug properties and PLGA characteristics is crucial for predictable drug delivery.

Keywords:
Drug propertyIn situ forming implantsMeloxicamNaproxenPLGA attributes

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