Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pulse rhythm

Pulse rhythm

Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...

Regulation of Pulse

Regulation of Pulse

Pulse regulation involves physiological mechanisms that ensure adequate blood flow throughout the body. The heartbeat, regulated by the autonomic nervous system, is influenced by hormonal balance, physical activity, and emotional state.

Special considerations while measuring pulse

Special considerations while measuring pulse

Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:

Special considerations while measuring blood pressure

Special considerations while measuring blood pressure

When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.

Assessment of radial pulse

Assessment of radial pulse

Assessment of Radial Pulse
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps:

Assessment of apical radial pulse

Assessment of apical radial pulse

Apical-Radial (A-R) Pulse Assessment
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Validation of Deep Capillary Plexus OCTA Metrics as Predictors of Diabetic Retinopathy Complications: A One-Year Longitudinal Study.

Research square·2026

Same author

Diminished transcriptional activity and splicing changes drive gene length-biased rewiring in the aging transcriptome.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Retinal Ischemic Perivascular Lesions Screen for Vision-Threatening Diabetic Retinopathy Visualized on Ultra-Widefield Fluorescein Angiography.

Translational vision science & technology·2026

Same author

Hypoxia-responsive interaction between P-TEFb, BHLHE40, and Tim8-Tim13 regulates hypoxic gene transcription.

Science advances·2026

Same author

Mitochondrial L-2-hydroxyglutarate is a physiological signalling metabolite.

Nature·2026

Same author

US Emergency Department Use and Operations Amid Natural Disasters: A Narrative Review.

The western journal of emergency medicine·2026

Search research articles

Related Experiment Video

Updated: May 7, 2025

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Published on: March 22, 2022

Systematic review: differences in complete blood count component rhythms.

Anna Busza¹, Vani Sharma², Kendall Ferguson³

¹Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Sleep Advances : a Journal of the Sleep Research Society

|December 30, 2024

Summary

This summary is machine-generated.

Complete blood count (CBC) reference values often ignore diurnal variations. This review found significant daily fluctuations in CBC components, with lymphocytes peaking overnight, highlighting the need for time-dependent interpretation in precision medicine.

Keywords:

biological rhythms circadian rhythm complete blood count diurnal rhythm reference values statistics

More Related Videos

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks

Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks

Published on: March 16, 2015

Related Experiment Videos

Last Updated: May 7, 2025

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Published on: March 22, 2022

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks

Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks

Published on: March 16, 2015

Area of Science:

Hematology
Clinical Pathology
Chronobiology

Background:

The complete blood count (CBC) is a routine diagnostic test with broad reference ranges.
Current interpretation of CBC values does not account for diurnal variations.
Understanding daily rhythms of CBC components is crucial for accurate clinical assessment.

Purpose of the Study:

To systematically review existing literature on the diurnal variation of complete blood count (CBC) parameters.
To identify peak and trough times for various CBC components.
To inform potential time-dependent interpretation of CBC results.

Main Methods:

Systematic literature search for studies with at least three CBC collections over 24 hours.
Screening of 164 full-text articles, with 32 included in the final analysis (548 patients).
Meta-analysis using polynomial functions and forest plots to analyze CBC component data.

Main Results:

Significant diurnal variations were observed across multiple CBC components.
Lymphocytes exhibited a distinct circadian rhythm, peaking overnight (23:54) and troughing in the morning (10:47).
Erythrocytes, hemoglobin, and hematocrit peaked in the morning; platelets, neutrophils, monocytes, and basophils peaked in the late afternoon.

Conclusions:

Limited studies characterize CBC component rhythms, but significant daily variations exist, particularly for lymphocytes.
Findings suggest the potential for time-dependent interpretation of CBC results.
Future research with larger datasets is needed to support precision medicine approaches.