Leptospirosis Causing Severe Acute Kidney Injury, Hyperbilirubinemia, and Thrombocytopenia: A Case Report

Leptospirosis, an infection caused by the spirochete Leptospira and commonly attributed to the underdeveloped world, is frequently under-diagnosed in the United States. This report discusses the case of a 79-year-old male with no significant medical history who presented to the ED with recurrent falls. Initial laboratory results demonstrated severe acute kidney injury, hyperbilirubinemia, and thrombocytopenia. Leptospirosis can mimic a wide variety of medical conditions, ranging from acalculous cholecystitis to alcoholic cirrhosis. Diagnosing leptospirosis requires an in-depth and detailed patient history. This case emphasizes the need for heightened awareness among healthcare providers to consider leptospirosis in their differential diagnoses.