Association of Helicobacter Pylori Infection with Functional Dyspepsia

Area of Science:

• Gastroenterology
• Infectious Diseases
• Microbiology

Background:

• Helicobacter pylori (H pylori) infection has been linked to dyspepsia for over 30 years.
• Functional dyspepsia is a common gastrointestinal disorder with varying underlying causes.
• Accurate diagnosis of H pylori infection is crucial for effective management of dyspepsia.

Purpose of the Study:

• To investigate the frequency of H pylori infection in patients diagnosed with functional dyspepsia.
• To assess the utility of stool antigen tests for detecting H pylori in this patient group.

Main Methods:

• 102 patients with functional dyspepsia, diagnosed via Rome IV criteria and normal upper GI endoscopy/ultrasonography, were included.
• H pylori infection was detected using stool antigen tests.
• Data on age, sex, and residence (rural/urban) were collected and analyzed.

Main Results:

• A 26.5% H pylori infection rate was detected among patients with functional dyspepsia.
• Prevalence was higher in women (29.0%) than men (21.2%), with the 30-39 age group showing the highest prevalence.
• No significant differences in H pylori positivity were observed based on age, sex, or residence.

Conclusions:

• The study indicates a notable rate of H pylori infection in patients presenting with functional dyspepsia.
• Stool antigen testing is a viable method for identifying H pylori in this population.
• Further research is warranted to establish the precise prevalence and clinical implications of H pylori in functional dyspepsia.