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Updated: Jun 4, 2025
A Murine Model of Muscle Training by Neuromuscular Electrical Stimulation
Published on: May 9, 2012
The additive effect of neuromuscular electrical stimulation and resistance training on muscle mass and strength
Gabriel Narvaez1, Jehu Apaflo1, Amy Wagler2
1Metabolic, Nutrition, and Exercise Research (MiNER) Laboratory, Department of Kinesiology, University of Texas at El Paso, 500 University Ave, El Paso, TX, 79968, USA.
Purpose:
To compare strength and muscle mass development between conventional resistance training (RT) and a combined resistance training with neuromuscular electrical stimulation group (RT + NMES).
Methods:
Searches of EBSCO, GoogleScholar, PubMed, and ResearchGate were conducted for studies that met the inclusion criteria of being a randomized controlled trial comparing RT in isolation with NMES and RT being done simultaneously. Effect sizes were calculated as the standard mean difference (SMD) and meta-analyses were computed using random effects models. Thirteen studies were included in the analyses.
Results:
When comparing strength gain, there was a favorable effect towards superimposed training (SMD: 0.31; 95% CI 0.13-0.49; p = 0.02; I2 = 73.05%) with similar results seen for muscle mass (SMD: 0.26; 95% CI 0.04-0.49; p = 0.02; I2 = 21.45%).
Conclusion:
Use of NMES during RT results in greater gains in strength and muscle mass compared to RT performed in isolation. Incorporation of NMES into RT protocols may represent a more effective strategy to improve muscle strength and muscle mass. Future studies should explore whether use of NMES concurrently with RT may have additive effects on metabolic and/or cardiovascular health.
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