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Social Determinants of Health Affecting Retinopathy of Prematurity Follow-up Attendance
Insights
Social determinants of health impact follow-up care for preterm infants with retinopathy of prematurity (ROP). Addressing these factors is crucial for improving vision health equity and adherence to ROP follow-up appointments.
Area of Science:
- Ophthalmology
- Public Health
- Neonatology
Background:
- Retinopathy of prematurity (ROP) is a leading cause of vision impairment in preterm infants.
- Consistent follow-up care after neonatal intensive care unit (NICU) discharge is critical for managing ROP and preventing vision loss.
- Social determinants of health (SDOH) can significantly influence healthcare access and adherence to medical recommendations.
Purpose of the Study:
- To identify social determinants of health (SDOH) associated with follow-up attendance for preterm infants diagnosed with retinopathy of prematurity (ROP).
- To analyze factors influencing ophthalmology follow-up adherence after neonatal intensive care unit (NICU) discharge.
Main Methods:
- Retrospective cohort study of preterm infants screened for ROP between July 2018 and December 2022.
- Sociodemographic and clinical data were extracted from a NICU database.
- Community-level SDOH indices were derived from residential ZIP codes; multivariable logistic regression analyzed follow-up attendance within 8 weeks to 1 year post-NICU discharge.
Main Results:
- Only 42% of patients attended follow-up within the specified interval.
- Higher odds of follow-up attendance were associated with private insurance, maternal non-Hispanic White identity, ROP treatment history, and longer NICU stays.
- An interaction effect showed privately insured patients had lower follow-up odds with increasing Social Vulnerability Index Racial and Ethnic Minority Status.
Conclusions:
- Individual and community-level SDOH significantly affect access to ROP follow-up care.
- The study highlights disparities in follow-up adherence, underscoring the need for targeted interventions.
- Improving vision health equity requires addressing SDOH to enhance follow-up adherence in ROP management.
Purpose:
To identify social determinants of health (SDOH) associated with follow-up attendance of pre-term infants with retinopathy of prematurity (ROP) after neonatal intensive care unit (NICU) discharge.
Methods:
This retrospective cohort study, conducted at a single academic tertiary care center, included preterm infants screened for ROP from July 2018 to December 2022. Sociodemographic and clinical data were collected from a preexisting NICU database. Residential ZIP code was used to derive community-level SDOH indices. Multivariable logistic regression was used to determine factors associated with ophthalmology follow-up attendance within 8 weeks to 1 year after NICU discharge.
Results:
Forty-two percent (303 of 723) of patients attended follow-up in the designated interval. Infants with private insurance (odds ratio [OR]: 4.47, 95% CI: 1.98 to 10.1, P < .001), maternal non-Hispanic White identity (OR: 1.80, 95% CI: 1.15 to 2.81, P = .01), ROP treatment history (OR: 3.67, 95% CI: 2.05 to 6.57, P < .001), and longer NICU stay (weeks) (OR: 1.06, 95% CI: 1.03 to 1.08, P < .001) had higher odds of attending follow-up. In an interaction effect, privately insured patients had lower odds of follow-up with each higher quartile of Social Vulnerability Index Racial and Ethnic Minority Status (OR: 0.61, 95% CI: 0.44 to 0.84, P = .002).
Conclusions:
Social determinants of health, including individual and community-level factors, significantly impact access to ROP follow-up. The identified disparities and overall inadequate follow-up rate suggest a need for targeted interventions to improve vision health equity and follow-up adherence. [J Pediatr Ophthalmol Strabismus. 2025;62(3):173-181.].
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