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Updated: Jun 4, 2025
![[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Visible-light-induced aerobic oxidative cyclization of nitroarenes with triethylamine using an organophotocatalyst
Yazheng Zhou1, Yutong He1, Huawen Huang1
1College of Chemistry, Xiangtan University, Xiangtan 411105, China. hwhuang@xtu.edu.cn.
Abstract:
Isoxazolidines are structurally important scaffolds in many natural products and bioactive compounds. Herein, we report a novel synthetic method for isoxazolidine derivatives through visible-light-induced photoredox cascade cyclization of nitroarenes with triethylamine under aerobic conditions. The resultant 5-hydroxyl isoxazolidine compounds were generally obtained in moderate yields with a broad range of compatible functionalities.
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