AIDS-related mycoses: advances, challenges, and future directions

Area of Science:

• Infectious Diseases
• Mycology
• Public Health

Background:

• Fungal infections are a leading cause of death in individuals with Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS).
• Significant progress has been made in reducing mortality from these infections.

Purpose of the Study:

• To address critical knowledge and management gaps in AIDS-related mycoses.
• To review recent scientific advancements and identify future research priorities.

Main Methods:

• Convening of experts including researchers, clinicians, industry professionals, and policymakers.
• Discussion and identification of scientifically driven milestones and unmet needs.

Main Results:

• Several key advancements have substantially decreased deaths attributed to fungal infections in the context of HIV/AIDS.
• Persistent challenges remain in the diagnosis, treatment, and research of AIDS-related mycoses.

Conclusions:

• Continued collaborative efforts are essential to overcome existing challenges in managing fungal infections in people with HIV/AIDS.
• Further research and improved diagnostic and therapeutic strategies are crucial to reduce the burden of AIDS-related mycoses.