Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

10.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
10.5K
Aging01:26

Aging

19
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
19

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Engineered PD1-NKG2D Dual-CAR NK92 cells broaden antitumor target recognition in preclinical tumor models.

Journal of translational medicine·2026
Same author

High speed slow-light Michelson interferometer modulators with dual-inductor peaking enhancement.

Optics express·2026
Same author

Optoelectronic co-simulation model for a 3D integrated structure with TSVs based on a micro-ring modulator and driver.

Applied optics·2026
Same author

High-throughput screening to engineer optimal T cell therapies: current knowledge and future prospects.

Frontiers in oncology·2026
Same author

Advances in research on thermogenic substances.

Journal of physiological anthropology·2026
Same author

Natural Products for Overcoming EGFR-TKI Resistance in NSCLC: A Narrative Review.

Anti-cancer agents in medicinal chemistry·2026

Related Experiment Video

Updated: May 7, 2025

Quantitative Imaging of Lineage-specific Toll-like Receptor-mediated Signaling in Monocytes and Dendritic Cells from Small Samples of Human Blood
07:58

Quantitative Imaging of Lineage-specific Toll-like Receptor-mediated Signaling in Monocytes and Dendritic Cells from Small Samples of Human Blood

Published on: April 16, 2012

35.0K

Propolis does not significantly modulate immune function in an older population: A preliminary study.

Lingling Pu1, Yonghui Wang1, Wei Pang1

  • 1Tianjin Institute of Environmental and Operational Medicine, Tianjin, 300050, China.

Heliyon
|January 6, 2025
PubMed
Summary
This summary is machine-generated.

This study found that Chinese propolis temporarily boosted immunoglobulin G (IgG) in the elderly, but immune function returned to normal levels over time. Propolis did not significantly alter other immune markers.

Keywords:
AntibodyCytokineLymphocytePropolis

More Related Videos

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
12:21

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Published on: September 28, 2022

2.3K
Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model
10:58

Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model

Published on: August 29, 2013

11.2K

Related Experiment Videos

Last Updated: May 7, 2025

Quantitative Imaging of Lineage-specific Toll-like Receptor-mediated Signaling in Monocytes and Dendritic Cells from Small Samples of Human Blood
07:58

Quantitative Imaging of Lineage-specific Toll-like Receptor-mediated Signaling in Monocytes and Dendritic Cells from Small Samples of Human Blood

Published on: April 16, 2012

35.0K
A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
12:21

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Published on: September 28, 2022

2.3K
Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model
10:58

Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model

Published on: August 29, 2013

11.2K

Area of Science:

  • Immunology
  • Gerontology
  • Natural Products Research

Background:

  • The elderly population faces increased susceptibility to infections due to age-related immune decline.
  • Propolis, a natural resinous mixture produced by honeybees, is known for its potential immunomodulatory properties.
  • Understanding the impact of natural compounds like propolis on aging immune systems is crucial for promoting health in older adults.

Purpose of the Study:

  • To investigate the effects of Chinese propolis supplementation on immune function in elderly individuals.
  • To assess changes in serum antibodies, cytokines, and cellular immune responses.

Main Methods:

  • A 12-week randomized controlled trial involving 62 community-dwelling elderly individuals (60-80 years) in Tianjin, China.
  • Participants received either 600 mg/day of Chinese propolis or a placebo.
  • Immune markers including serum antibodies (e.g., IgG), cytokines, lymphocyte proliferation (MTT assay), and neutrophil function (Staphylococcal method) were measured.

Main Results:

  • A transient increase in Immunoglobulin G (IgG) levels was observed at week 6 in the propolis group, which returned to baseline by week 12.
  • No significant differences were found in other measured serum antibodies, cytokines, lymphocyte, or neutrophil functions between the propolis and control groups throughout the study.
  • Dietary intake was assessed using a 24-hour recall method.

Conclusions:

  • Chinese propolis demonstrated a short-term stimulatory effect on IgG secretion in the elderly.
  • The observed immune effects of propolis were temporary, with levels reverting to baseline over the 12-week study period.
  • Propolis supplementation did not yield significant long-term or broad-spectrum improvements in the immune markers assessed in this elderly cohort.