Management of Lower Urinary Tract Symptoms during the Treatment for Non-Muscle Invasive Bladder Cancer
Benjamin Seiden1, Divya Ajay2, Felix Cheung2
1Department of Urology, Kings County Hospital Center, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.
Managing lower urinary tract symptoms (LUTS) during cancer treatment shows promise with new strategies. Further research is needed to confirm the effectiveness of these emerging therapies for LUTS.
Area of Science:
- Urology
- Oncology
- Pharmacology
Background:
- Lower urinary tract symptoms (LUTS) are common side effects of cancer treatments like transurethral resection and intravesical therapy.
- Effective management of LUTS is crucial for patient quality of life and treatment adherence.
Purpose of the Study:
- To review current evidence and strategies for managing LUTS during cancer treatment.
- To examine novel approaches for mitigating treatment-related LUTS and improving adherence.
Main Methods:
- Narrative review of existing literature.
- Examination of current and emerging treatment evidence for LUTS.
Main Results:
- Sparse but promising evidence exists for improving LUTS secondary to intravesical therapy.
- Oral agents, Bacillus Calmette-Guerin dose reduction, beta-3 agonists, and Onabotulinumtoxin A injections show encouraging results in limited studies.
- Further research is required to establish efficacy and consensus on treatment strategies for intravesical therapy-related LUTS.
Conclusions:
- Emerging therapies show potential for managing LUTS during cancer treatment.
- More research is needed to validate these strategies and develop new treatment guidelines for LUTS.
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