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Postpartum hemorrhage assessment and targeted treatment

Allison A Mootz1, John J Kowalczyk2, Sebastian M Seifert2

  • 1Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02115, USA; Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center & Parkland Memorial Hospital, 5323 Harry Hines Blvd, Dallas, Texas, 75390, USA.

Best Practice & Research. Clinical Anaesthesiology
|January 7, 2025
PubMed

Postpartum hemorrhage (PPH) is the leading cause of maternal mortality worldwide, and mitigating it is a global health priority. In this review, we discuss the measurement, assessment, and treatment of PPH. We review different methods of quantifying blood loss, including gravimetry, calibrated drapes and canisters, and colorimetric techniques. Additionally, we highlight the importance of obstetric-specific massive transfusion protocols, point-of-care coagulation testing, and the role of fibrinogen and tranexamic acid. Lastly, we review placenta accreta spectrum management. Anesthesiologists are critical participants in the management of PPH, ultimately influencing patient outcomes.

Keywords:
Blood transfusionFibrinogenMaternal mortalityPlacenta accretaPoint-of-care systemsPostpartum hemorrhageTranexamic acid

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