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Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

490
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
490

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Updated: Jun 3, 2025

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
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Methodological Variation Among Studies Evaluating Pain Processing in Tendinopathy: A Scoping Review.

Dhinu Jayaseelan1, Andrew Post2, Josiah Sault3

  • 1Program in Physical Therapy, The George Washington University, Washington, DC 20006, USA.

Journal of Clinical Medicine
|January 8, 2025
PubMed
Summary
This summary is machine-generated.

This review found significant variability in how pain processing in tendinopathy is studied. Standardizing methods is crucial for reliable clinical guidance on tendon pain.

Keywords:
pain assessmentphysical therapysensitizationtendon

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Area of Science:

  • Musculoskeletal Research
  • Pain Science
  • Clinical Methodology

Background:

  • Tendinopathy causes pain and functional limitations.
  • Potential differences in pain processing exist between upper and lower extremity tendinopathies.
  • Current research shows varying patterns of dysfunction in pain inhibition.

Purpose of the Study:

  • To conduct a scoping review of methods used in studies examining pain processing in tendinopathy.
  • To analyze and compare methodologies across upper and lower extremity tendinopathy research.
  • To identify inconsistencies and areas for improvement in tendon pain research.

Main Methods:

  • Searched five electronic databases and gray literature up to April 15, 2024.
  • Included studies examining pain processing in upper and lower extremity tendinopathy.
  • Analyzed 43 studies focusing on methodology, patient demographics, and reported outcomes.

Main Results:

  • Most studies used pressure pain thresholds to assess nervous system sensitization.
  • Significant variation exists in testing modes, instruments, and reporting of patient demographics.
  • Over 70% of studies reported evidence of nervous system sensitization or dysfunction in tendinopathy.

Conclusions:

  • Methodological inconsistencies and reporting variability are prevalent in tendinopathy pain research.
  • Standardization of research methods is needed to enhance clinical applicability and guidance.
  • Further efforts are warranted to improve the consistency and reliability of tendon pain studies.