Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clear cell myeloma.

K T Chen, C K Ma, J W Nelson

    The American Journal of Surgical Pathology
    |February 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Clear cell myeloma can be mistaken for liposarcoma due to clear cell appearance. This case highlights distinguishing features for accurate diagnosis of this rare plasma cell neoplasm.

    Related Experiment Videos

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Anomalous vertebral artery course causing radiculopathy: A case report and review of relevant literature.

    Brain & spine·2026
    Same author

    Lymphadenoma.

    The Chicago medical journal and examiner·2023
    Same author

    Generative Adversarial Network-Enhanced Ultra-Low-Dose [<sup>18</sup>F]-PI-2620 τ PET/MRI in Aging and Neurodegenerative Populations.

    AJNR. American journal of neuroradiology·2023
    Same author

    Investigating Simultaneity for Deep Learning-Enhanced Actual Ultra-Low-Dose Amyloid PET/MR Imaging.

    AJNR. American journal of neuroradiology·2022
    Same author

    The Effect of Breast Cancer Subtype on Symptom Improvement Following Palliative Radiotherapy for Bone Metastases.

    Clinical oncology (Royal College of Radiologists (Great Britain))·2021
    Same author

    Anti-PF4 VITT antibodies are oligoclonal and variably inhibited by heparin.

    medRxiv : the preprint server for health sciences·2021
    Same journal

    Clinicopathologic and Molecular Analysis of Traditional Serrated Adenoma and Its Possible Precursor Lesions With Special Reference to RSPO Fusion Status: A Large Case Series From Single Institution.

    The American journal of surgical pathology·2026
    Same journal

    NF2/Merlin Immunohistochemistry Helps Distinguish Collecting Duct Carcinoma From Upper Tract Urothelial Carcinoma.

    The American journal of surgical pathology·2026
    Same journal

    Neuroendocrine Carcinoma of the Gallbladder: Clinicopathologic and Immunohistochemical Analysis of 31 Cases.

    The American journal of surgical pathology·2026
    Same journal

    Papillary Renal Neoplasm With Reverse Polarity Is a Distinct Distal Nephron-Derived Tumor With Unique Methylation Profile.

    The American journal of surgical pathology·2026
    Same journal

    Biallelic ARID1A Alterations: A Promising Novel Biomarker for Risk Stratification and Management in Pediatric Malignant Hepatocellular Tumors.

    The American journal of surgical pathology·2026
    Same journal

    Absent Cyclin D1 Expression in Myeloid Sarcomas Distinguishes From Malignant Histiocytic Neoplasms: When Morphologic Ambiguity is Deceptive.

    The American journal of surgical pathology·2026
    See all related articles

    Area of Science:

    • Oncology
    • Pathology
    • Hematology

    Background:

    • Clear cell myeloma is a rare variant of plasma cell myeloma.
    • It can present with features that mimic other tumors, leading to diagnostic challenges.

    Observation:

    • A patient presented with lytic skeletal lesions and monoclonal immunoglobulin A (IgA), kappa.
    • Initial biopsy misinterpreted the clear cell myeloma as liposarcoma due to cytoplasmic vacuoles.

    Findings:

    • Histologic examination revealed tumor cells with cytoplasmic vacuoles, creating a clear appearance.
    • Light microscopy and ultrastructural analysis were crucial for differentiating it from liposarcoma and other lymphoplasmacytic disorders.

    Implications:

    • Accurate diagnosis of clear cell myeloma is essential for appropriate treatment and patient management.
  • Awareness of this entity and its potential for misinterpretation can improve diagnostic accuracy in challenging cases.