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Prediction of SPT-07A Pharmacokinetics in Rats, Dogs, and Humans Using a Physiologically-Based Pharmacokinetic Model

Xiaoqiang Zhu1, Weimin Kong2, Zehua Wang1

  • 1Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China.

Pharmaceutics
|January 8, 2025
PubMed

Keywords:
SPT-07AUDP-glucuronosyltransferasescytochrome P450interspecies allometric scalingischemic strokephysiologically-based pharmacokinetic modelunbound fraction in plasma

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