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Updated: Jun 3, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Metal-Free Electrochemical Allylic C-H Aerobic Oxidation
Tong Shen1, Jianyou Zhao2, Xuanxuan Ren1
1College of Pharmaceutical Engineering, Jiangsu Food & Pharmaceutical Science College, Huaian 210023, China.
Abstract:
A scalable and sustainable electrochemical protocol for allylic C-H aerobic oxidation has been developed, enabling the formation of enones without the use of stoichiometric toxic oxidants or metal catalysts and offering an environmentally benign alternative to traditional chemical oxidation techniques. The process has been successfully applied to selectively oxidize a series of natural products and drug molecules, underscoring its potential for widespread adoption in both academic and industrial contexts.
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