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Updated: Jul 26, 2026

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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
A probable case of rotavirus exanthem
Archives of Dermatology
|February 1, 1985
Summary
Rotavirus gastroenteritis in children can lead to a generalized rash and hepatitis in adult men. This study suggests rotavirus as a cause of exanthem in adults, supported by serological evidence.
Area of Science:
- Virology
- Dermatology
- Hepatology
Background:
- Rotavirus is a common cause of gastroenteritis in children.
- Extraintestinal manifestations of rotavirus are rare in adults.
Observation:
- A 28-year-old man developed a generalized maculopapular exanthem and hepatitis.
- Symptoms appeared one week after his sons recovered from rotavirus gastroenteritis.
Findings:
- The patient's serum showed high rotavirus antibody titers (1:256 and 1:512).
- Other causes of exanthemata were ruled out through clinical and laboratory tests.
Implications:
- This case suggests rotavirus infection can cause exanthem and hepatitis in adults.
- Highlights the importance of considering rotavirus in adult patients with similar symptoms.
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