A New Method to Measure Ocular Surface Sensitivity: Repeatability and Reproducibility of the Liquid Jet Esthesiometer
Klaus Ehrmann1, Cristian Talens-Estarelles, Fiona Stapleton
1School of Optometry and Vision Science (K.E., F.S., B.T., J.C., B.G.), University of New South Wales, Sydney, Australia; and Department of Optics and Optometry and Vision Sciences (C.T.-E.), University of Valencia, Valencia, Spain.
Eye & Contact Lens
|January 8, 2025
Summary
The liquid jet esthesiometer (LJA) reliably measures corneal sensitivity, showing good repeatability within sessions and moderate reproducibility between sessions. This tool is effective across various population groups and stimulus thresholds.
Area of Science:
- Ophthalmology
- Neuroscience
- Biomedical Engineering
Background:
- Corneal sensitivity is crucial for ocular surface health and protective reflexes.
- Accurate measurement of corneal sensitivity is essential for diagnosing and managing various ocular conditions.
Purpose of the Study:
- To evaluate the clinical reliability of the liquid jet esthesiometer (LJA) for measuring corneal sensitivity.
- To assess both intrasession repeatability and intersession reproducibility of the LJA.
Main Methods:
- Two studies were conducted: Study 1 assessed intrasession repeatability, and Study 2 assessed intersession reproducibility.
- Participants' corneal sensation thresholds were measured multiple times using the LJA, with variations in timing and examiners.
Main Results:
- The LJA demonstrated good intrasession repeatability (ICC 0.74) and moderate intersession reproducibility (CVw 32%).
- Corneal sensitivity thresholds were significantly lower in female participants compared to males (P=0.02).
- Measurement variability was not influenced by the stimulus threshold level (P=0.84).
Conclusions:
- The liquid jet esthesiometer (LJA) is a reliable tool for assessing corneal sensitivity in diverse populations.
- Good clinical repeatability suggests the LJA is suitable for routine use, though day-to-day fluctuations may affect reproducibility.
