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Updated: Jun 19, 2026
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Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies
Published on: November 27, 2013
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Micro- and milli-fluidic sample environments for in situ X-ray analysis in the chemical and materials sciences
Mark A Levenstein1, Corinne Chevallard1, Florent Malloggi1
1Université Paris-Saclay, CEA, CNRS, NIMBE, LIONS, 91191, Gif-sur-Yvette, France. mark.levenstein@cea.fr.
Lab on a Chip
|January 8, 2025
Summary
Microfluidic and millifluidic platforms enhance X-ray analysis for materials and chemical sciences, enabling high-resolution, time-resolved studies of liquid samples. This review covers advancements in X-ray scattering, spectroscopy, and imaging, including lab-based systems.
Area of Science:
- Materials Science
- Chemical Science
- Analytical Chemistry
Background:
- X-ray-based methods are crucial for material and chemical studies, especially for time-resolved measurements.
- Microfluidic and millifluidic platforms offer enhanced temporal and spatial resolution for X-ray analysis.
- Previous research primarily utilized synchrotron facilities for microfluidic X-ray analysis.
Purpose of the Study:
- To review advancements in X-ray compatible microfluidic and millifluidic platforms.
- To highlight applications in X-ray scattering/diffraction, spectroscopy, and imaging for liquid samples.
- To discuss the emerging use of laboratory-based X-ray instruments for these techniques.
Main Methods:
- Review of microfluidic and millifluidic device development for X-ray analysis.
- Focus on techniques including X-ray scattering, spectroscopy, and imaging.
- Analysis of applications for liquid samples and suspensions.
Main Results:
- Significant progress in developing microfluidic and millifluidic platforms for X-ray analysis.
- Demonstrated utility across scattering, spectroscopy, and imaging techniques.
- Emerging use of commercial and laboratory-based X-ray instruments, expanding accessibility.
Conclusions:
- Microfluidic and millifluidic X-ray analysis enables high-resolution studies of materials and chemical processes.
- The integration of laboratory-based X-ray sources is transforming accessibility and routine application.
- These platforms are poised to become standard methods in physical chemistry and materials research.
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