Related Experiment Video

Updated: Jun 3, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

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Cell-Active, Arginine-Targeting Irreversible Covalent Inhibitors for Non-Kinases and Kinases

Peng Chen1,2, Lu Wang3, Xuan Wang1,4

  • 1Department of Chemistry, National University of Singapore, Singapore, 117543, Singapore.

Angewandte Chemie (International Ed. in English)
|January 8, 2025
PubMed
Abstract

Keywords:
Kinaseargininecovalent inhibitorglyoxalprodrug

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