Related Experiment Video

Updated: Jun 3, 2025

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

17.1K

Clinical Characteristics and Outcomes of Deep Vein Thrombosis in Relation to Location: A Retrospective Analysis Study

Majed S Al Yami1,2,3, Abdulmajeed M Alshehri1,2,3, Ghadah M Alotaibi1

  • 1Department of Pharmacy Practice, College of Pharmacy, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
|January 9, 2025
PubMed

Insights

Deep vein thrombosis (DVT) classification into isolated distal (iDDVT), isolated proximal (iPDVT), or mixed types showed similar long-term outcomes. Baseline characteristics did not significantly predict DVT type, with leg injury being higher in iDDVT.

Area of Science:

  • Medical research
  • Vascular medicine
  • Thrombosis

Background:

  • Deep vein thrombosis (DVT) is a significant cause of mortality and morbidity.
  • DVT classification includes isolated distal DVT (iDDVT), isolated proximal DVT (iPDVT), and mixed DVT.
  • Understanding differences in baseline characteristics and outcomes across DVT types is crucial for patient management.

Purpose of the Study:

  • To investigate the baseline characteristics of patients with different DVT classifications.
  • To assess and compare clinical outcomes, including recurrent DVT, major bleeding, rehospitalization, and mortality, among iDDVT, iPDVT, and mixed DVT groups.

Main Methods:

  • Retrospective study analyzing data from 493 patients experiencing their first DVT event.
  • Patients were categorized into iDDVT, iPDVT, or mixed DVT groups based on clot location and extent.
  • Outcomes assessed included recurrent DVT, major bleeding (MB), VTE-related rehospitalization, and DVT-related inpatient mortality at 12 months.

Main Results:

  • The study included 273 (55.4%) iPDVT, 25 (5.1%) iDDVT, and 195 (39.6%) mixed DVT patients.
  • Leg injury was a significantly more common etiology in iDDVT (24%) compared to iPDVT (6.2%) and mixed DVT (5.6%).
  • At 12 months, overall recurrent DVT was 9.9%, with similar rates across groups (iPDVT 9.2%, iDDVT 12.0%, mixed DVT 10.8%). Rates of MB, re-hospitalization, and DVT-related death were also similar.

Conclusions:

  • No significant association was found between baseline characteristics and the development of specific lower extremity DVT types.
  • Clinical outcomes, including recurrence, bleeding, rehospitalization, and mortality, are comparable across isolated distal, isolated proximal, and mixed DVT classifications.

Keywords:
deep vein thrombosisdistal and proximal DVTrecurrent DVTvenous thromboembolism (VTE)

More Related Videos

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis06:45

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Published on: February 10, 2023

12.8K
Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane08:05

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Published on: December 9, 2022

3.9K

Related Concept Videos

Venous Return01:04

Venous Return

The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
2.9K
Veins of Lower Limbs01:15

Veins of Lower Limbs

The human body consists of an intricate network of veins responsible for the crucial task of blood drainage from the lower limbs. These veins can be categorized into two main types: deep veins and superficial veins.
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the...
598
Assessment of the Cardiovascular System III: Palpation01:27

Assessment of the Cardiovascular System III: Palpation

Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
189
Pulse Assessment Sites01:11

Pulse Assessment Sites

Pulse assessment sites are crucial in evaluating a patient's cardiovascular health. By assessing the pulsations of arteries at specific anatomical locations, healthcare professionals can gather valuable information about blood flow, heart rate, and peripheral circulation. Understanding these pulse assessment sites is essential for conducting comprehensive cardiovascular evaluations and monitoring patients' overall health. These sites are strategically chosen due to the accessibility and...
917
Overview of Systemic Veins01:11

Overview of Systemic Veins

Systemic veins are crucial blood vessels that return deoxygenated blood from various body tissues back to the heart. There are three systemic veins that return deoxygenated blood to the heart, they are as follows.
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the...
431