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Related Experiment Videos

Dactylitis in a child with sickle cell trait.

T Jadavji, C G Prober

    Canadian Medical Association Journal
    |April 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Dactylitis, a painful swelling of the fingers and toes, is rare in sickle cell trait. This case suggests severe diarrhea and dehydration may trigger dactylitis in individuals with sickle cell trait.

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    Area of Science:

    • Hematology
    • Pediatrics
    • Genetics

    Background:

    • Dactylitis is a common manifestation in severe hemoglobinopathies like sickle cell anemia.
    • It is typically observed in homozygous hemoglobin S disease, sickle cell-hemoglobin C disease, and sickle cell-beta-thalassemia.

    Observation:

    • A rare case of dactylitis is reported in a patient with sickle cell trait.
    • Sickle cell trait is generally considered benign, with dactylitis being an exceptionally uncommon complication.

    Findings:

    • The patient presented with dactylitis, a condition usually associated with more severe sickle cell disorders.
    • The occurrence in sickle cell trait suggests potential alternative or co-existing factors contributing to the vaso-occlusive event.

    Implications:

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    • This case highlights that dactylitis can occur even in sickle cell trait under specific circumstances.
    • Severe diarrhea and dehydration are proposed as potential precipitating factors for dactylitis in this context.
    • Further investigation is warranted to understand the pathophysiology of dactylitis in sickle cell trait and identify potential triggers.