Related Experiment Video
Updated: Jun 3, 2025

A Non-Invasive Method for Generating the Cyclic Loading-Induced Intra-Articular Cartilage Lesion Model of the Rat Knee
Published on: July 5, 2021
Comparative analysis of isokinetic parameters in individuals with and without chondromalacia patellae
Thiago Resende Inojossa1, Angelica Castilho Alonso2, Vanderlei Carneiro da Silva3
1Laboratory Study of Movement, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas (IOT-HC), Faculdade de Medicina, Universidade de São Paulo (FMSUP), São Paulo, SP, Brazil.
Introduction:
Chondromalacia patella (CMP) is characterizsed by cartilage degeneration, affects young adults, more women (2:1) and is responsible for 75% of knee pain complaints in the active population. The etiology is multifactorial and may be related to extrinsic factors (trauma and burden) and intrinsic factors (patellar malalignment and quadriceps weakness). Isokinetic dynamometry (ID) can aid in the detection of the causal factors of knee pain related to CMP.
Objectives:
To evaluate and compare the parameters of the ID of individuals with and without CMP and correlate them with the clinical aspects of individuals with CMP.
Methods:
This is a retrospective study that analyzed ID of the knee flexors and extensors, performed between 2013 and 2019 in the isokinetic dynamometry sector of the hospital. Six hundred ninety dynamometers tests were included, both sexes, aged between 14 and 59 years, divided into chondromalacia group (342) tests and control group (348) tests. All performed ID in concentric mode for knee extension and flexion, with five maximum repetitions at an angular speed of 60°/s and 180°/s and 20 repetitions at an angular speed of 300°/s, with 30-s intervals between each. After completing the test, the patient points out a number from 0 to 10 on the visual analog scale, regarding the presence and intensity of pain during and after the isokinetic assessment.
Results:
The groups had similar distribution from sex (P = 0.071); age (P = 0.99) but were different about pain (P < 0.001). CMP had greater levels of pain. In most of the muscle parameters of the extensors and flexors at 60°/s were lower in the CMP group (P < 0.001).
Conclusion:
The main predictor of chondromalacia is pain. The greater coefficient of variability and time to reach peak torque on the involved side, the average power and morphology of the extensor curve can also be predictors of chondromalacia.
Level Of Evidence:
III.
More Related Videos
08:26Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running
Published on: July 17, 2020
08:42Real-time Visualization and Analysis of Chondrocyte Injury Due to Mechanical Loading in Fully Intact Murine Cartilage Explants
Published on: January 7, 2019