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Updated: Jun 3, 2025

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation
Published on: January 17, 2011
Extracorporeal Membrane Oxygenation Without Mechanical Ventilation for Recovery From Tracheal Repair
Sheel Patel1, Daniel K Mohammadi1, Clinton T Morgan1
1Division of Cardiothoracic Surgery, Department of Surgery, University of Kentucky, Lexington, Kentucky.
This study presents a novel approach for airway repair by using prolonged venovenous extracorporeal membrane oxygenation (ECMO) instead of positive pressure ventilation (PPV). This method supports healing in complex intrathoracic airway injuries.
Area of Science:
- Thoracic surgery
- Critical care medicine
- Respiratory physiology
Background:
- Large intrathoracic airway repairs are challenging.
- Postoperative positive pressure ventilation (PPV) can impede healing of these repairs.
- Severe emphysema poses additional risks for airway management.
Observation:
- A 67-year-old woman with severe emphysema sustained a full-length transmural intrathoracic tracheal intubation injury.
- Following surgical repair, the patient could not tolerate extubation or PPV distal to the repair site.
- Mediastinitis complicated the postoperative course.
Findings:
- Prolonged venovenous extracorporeal membrane oxygenation (ECMO) was initiated for 13 days.
- ECMO provided oxygenation and ventilation support without the need for PPV.
- This allowed for unimpeded healing of the large airway repair.
Implications:
- This case demonstrates a potentially life-saving alternative to PPV in specific complex airway reconstructions.
- Venovenous ECMO may be a valuable tool for managing patients with intrathoracic airway injuries who cannot tolerate conventional ventilation.
- Further research is warranted to explore the broader applicability of this technique in thoracic surgery and critical care.
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