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Updated: Jun 3, 2025

In Vitro Thrombosis Test for Ventricular Assist Devices
Published on: March 21, 2025
Variations in Perioperative Thromboprophylaxis Practices: Do the Guidelines Need a Closer Look?
Russell Seth Martins1, Elizabeth Christophel2, Kostantinos Poulikidis1
1Division of Thoracic Surgery, Department of Surgery, Hackensack Meridian Health Network, Hackensack, New Jersey.
Most US thoracic surgeons deviate from 2022 guidelines on VTE prophylaxis for cancer patients. Extended postoperative prophylaxis is rarely used, suggesting a need to re-evaluate current practices and explore new agents.
Area of Science:
- Thoracic Surgery
- Oncology
- Vascular Surgery
Background:
- Joint guidelines for perioperative venous thromboembolism (VTE) prophylaxis in thoracic cancer patients were issued by the AATS and ESTS in 2022.
- This study assesses adherence to these guidelines one year post-publication.
Purpose of the Study:
- To evaluate current practices in VTE prophylaxis among US thoracic surgeons.
- To determine the extent of adherence to the 2022 AATS/ESTS guidelines.
Main Methods:
- A survey was conducted among board-certified/eligible thoracic surgeons in the US.
- Data were collected between July and October 2023.
Main Results:
- Over half of 103 surveyed surgeons routinely use preoperative chemical VTE prophylaxis.
- The majority limit postoperative prophylaxis to hospital stay, rarely extending it post-discharge.
- Low-molecular-weight heparin (LMWH) is the preferred agent for extended prophylaxis when used.
Conclusions:
- Most US thoracic surgeons do not routinely prescribe extended postoperative VTE prophylaxis, contrary to 2022 guidelines.
- The need for reevaluation of extended thromboprophylaxis is highlighted due to enhanced recovery in minimally invasive surgery.
- Further research, including RCTs on extended prophylaxis and newer agents like DOACs, is warranted.
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