Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The Finn chamber methylene blue ring.

T Fischer, H Maibach

    Contact Dermatitis
    |January 1, 1985
    PubMed
    Summary

    Metallic aluminium reacts with methylene blue on skin, creating a unique, strong coloration. This interaction demonstrates aluminium is not inert and may affect patch test results.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pathophysiology and management of sensitive skin: position paper from the special interest group on sensitive skin of the International Forum for the Study of Itch (IFSI).

    Journal of the European Academy of Dermatology and Venereology : JEADV·2019
    Same author

    Comparing touch senses of naïve and expert panels through treated hair swatches: which associated wordings correlate with hair physical properties?

    International journal of cosmetic science·2017
    Same author

    Skin absorption through atopic dermatitis skin: a systematic review.

    The British journal of dermatology·2016
    Same author

    Physiological effect of olfactory stimuli inhalation in humans: an overview.

    International journal of cosmetic science·2013
    Same author

    Metabolic enzyme activities and drug excretion in the small intestine and in the liver in the rat.

    Acta physiologica Hungarica·2013
    Same author

    Characterization of focal breast lesions by means of elastography.

    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin·2013

    Area of Science:

    • Dermatology
    • Materials Science
    • Biochemistry

    Background:

    • Metallic aluminium is commonly used in medical devices and consumer products.
    • Methylene blue is a dye with various applications, including in diagnostic procedures.
    • The interaction between metallic aluminium and organic compounds on human skin is not well understood.

    Purpose of the Study:

    • To investigate the interaction between metallic aluminium and methylene blue when applied to human skin.
    • To determine if this interaction produces a unique observable effect.
    • To assess the potential reactivity of metallic aluminium in dermatological testing.

    Main Methods:

    • Metallic aluminium and methylene blue were applied to human skin.
    • The resulting coloration was observed and characterized.
    • Control experiments using methylene blue alone and other dyes were performed.

    Main Results:

    • A strong, resistant coloration was observed when metallic aluminium and methylene blue were combined on the skin.
    • Methylene blue alone or with other dyes did not produce the same coloration.
    • This indicates a specific chemical interaction between metallic aluminium and methylene blue.

    Conclusions:

    • Metallic aluminium is not an inert material when in contact with human skin.
    • The observed reaction suggests that aluminium in patch test chambers may interact with other test substances.
    • Further research is warranted to explore the implications of this reactivity in patch testing and material biocompatibility.

    Related Experiment Videos