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Updated: Jun 3, 2025

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Quantitative Myocardial Perfusion in Surgically Repaired Coronary Artery Anomaly
Shiro Miura1, Atsutaka Okizaki2, Osamu Manabe3
1Department of Cardiology, Hokkaido Ohno Memorial Hospital, Sapporo, Japan.
Insights
An anomalous origin of the right coronary artery can cause heart ischemia, requiring surgery. Surgical repair significantly improved symptoms and myocardial blood flow, though imaging interpretation was challenging.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Imaging
Background:
- Anomalous aortic origin of the right coronary artery (AORCA) with an intramural course is a rare congenital heart defect.
- This anomaly can lead to myocardial ischemia and angina, necessitating surgical intervention.
Abstract:
The anomalous aortic origin of the right coronary artery with an intramural course is rare and can cause myocardial ischemia, for which surgical repair is indicated. We present the case of a 49-year-old man with this anomaly whose preoperative myocardial perfusion positron emission tomography revealed inducible ischemia. Comparison of the preoperative and follow-up (6 months) positron emission tomography findings showed significant improvement in regional myocardial flow reserve and relative flow reserve, in keeping with the improvement in symptoms. However, positron emission tomography/myocardial perfusion imaging findings were difficult to interpret.

