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A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse

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Neonatal Gerbode Defect Resulting in Cardiogenic Shock.

Lillian Kang¹, Anna C Hoover², Michael Camitta³

¹Department of Surgery, Duke University Medical Center, Durham, North Carolina.

Annals of Thoracic Surgery Short Reports

|January 10, 2025

Summary

A rare congenital Gerbode defect in a neonate caused severe heart problems and cardiogenic shock. Surgical repair led to a full recovery, highlighting the importance of timely intervention for this uncommon condition.

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Area of Science:

Cardiology
Pediatric Cardiology
Congenital Heart Disease

Background:

Congenital Gerbode defects involve a rare membranous septum deficiency causing left ventricle-to-right atrium shunting.
These defects are typically not hemodynamically significant.

Observation:

A neonate presented with a large, unrestrictive Gerbode defect, patent foramen ovale, patent ductus arteriosus, and pulmonary valve insufficiency.
This complex anatomy resulted in a circular intracardiac shunt and severe cardiogenic shock.

Findings:

The neonate required venoarterial extracorporeal membrane oxygenation for stabilization.
Successful surgical repair of the neonatal Gerbode defect was performed.

Implications:

This case highlights an exceedingly rare presentation of congenital Gerbode defect causing cardiogenic shock in a neonate.
Prompt diagnosis and surgical intervention are crucial for managing such complex congenital heart anomalies.
Successful management underscores the potential for favorable outcomes with timely treatment.