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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis II01:28

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Hearing01:31

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When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
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Updated: Jun 3, 2025

Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct
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[When tuberculosis makes you deaf].

V Cauhape1, K Risso2, E Demonchy1

  • 1Service des maladies infectieuses et tropicales, hôpital Archet, 151, route Saint-Antoine de Ginestière, 06202 Nice cedex, France.

Revue Des Maladies Respiratoires
|January 10, 2025
PubMed
Summary
This summary is machine-generated.

Tuberculous otomastoiditis, a rare infection, was diagnosed late in a patient with necrotising otitis externa (NOE). This case highlights the diagnostic challenge posed by co-occurring infections, emphasizing the need for vigilance in complex otologic cases.

Keywords:
Necrotizing otitis externaOtite maligne externeOtite moyenne tuberculeuseOtomastoïdite tuberculeusePseudomonas aeruginosaTuberculous otitis mediaTuberculous otomastoiditis

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Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Microbiology

Background:

  • Tuberculous otomastoiditis is a rare but severe infection, often linked to pulmonary tuberculosis.
  • Necrotising otitis externa (NOE) caused by Pseudomonas aeruginosa is a distinct otologic emergency.
  • Co-infection of these conditions presents diagnostic and therapeutic challenges.

Purpose of the Study:

  • To report an exceptional case of co-existing tuberculous otomastoiditis and Pseudomonas aeruginosa necrotising otitis externa.
  • To highlight the diagnostic delay caused by the initial presentation of NOE.
  • To underscore the importance of considering rare pathogens in refractory otologic infections.

Main Methods:

  • Case report of a 50-year-old patient with NOE and concurrent pulmonary tuberculosis.
  • Clinical evaluation including temporal bone imaging showing lysis and carotid canal involvement.
  • Surgical intervention (mastoidectomy) for abscess drainage and microbiological analysis (PCR) for tuberculosis complex detection.

Main Results:

  • The patient presented with NOE and pulmonary tuberculosis, complicated by temporal bone lysis.
  • Despite initial treatment for NOE, the condition progressed, necessitating mastoidectomy.
  • Tuberculosis complex was confirmed via PCR from deep tissue samples, leading to treatment for both pulmonary and osseous tuberculosis.
  • While treatment led to a favorable clinical course, the patient experienced subsequent deafness.

Conclusions:

  • The simultaneous occurrence of Pseudomonas aeruginosa NOE and tuberculous otomastoiditis is exceedingly rare.
  • Necrotising otitis externa can mask or delay the diagnosis of underlying tuberculous otomastoiditis.
  • Prompt and comprehensive microbiological investigation is crucial for managing complex otologic infections.