Nutrient Intake and Dietary Adequacy Among Rural Tanzanian Infants Enrolled in the Mycotoxin Mitigation Trial
Rosemary A Kayanda1, Neema Kassim1, Francis M Ngure2
1Department of Food Sciences and Biotechnology, School of Life Sciences and Bioengineering, The Nelson Mandela African Institution of Science and Technology (NM-AIST), Arusha P.O. Box 447, Tanzania.
Nutrients
|January 11, 2025
Summary
Dietary aflatoxin (AF) mitigation in the Mycotoxin Mitigation Trial (MMT) showed no differences in infant energy, lipid, or micronutrient intake between arms. Protein intake was slightly higher in the intervention arm, supporting trial validity.
Area of Science:
- Nutrition Science
- Public Health Research
- Clinical Trials
Background:
- The Mycotoxin Mitigation Trial (MMT) investigated dietary aflatoxin (AF) effects on linear growth.
- Ensuring similar dietary intake between trial arms was crucial for MMT's validity and interpretation.
Purpose of the Study:
- To assess and compare infant dietary intake between intervention and standard of care arms within the MMT.
- To evaluate nutrient intake and adequacy in infants at the trial's midpoint.
Main Methods:
- A sub-sample of 20 clusters from the MMT was analyzed.
- One-time, 24-hour dietary recalls were conducted for 282 maternal/infant dyads at 12 months of age.
- Mixed-level regression models analyzed nutrient intake differences between arms.
Main Results:
- No significant differences were found in mean daily energy (505 kcal/day) and lipid (13 g/day) intake between arms.
- Infants in the intervention arm consumed slightly more protein (13.7 g/day) than the standard of care arm (12.3 g/day, p=0.02).
- Intake of iron, zinc, calcium, and vitamin A was low and did not differ between the intervention and standard of care arms.
Conclusions:
- Infant energy, lipid, and key micronutrient intake were comparable between MMT arms at the midpoint.
- Slightly higher protein consumption in the intervention arm was observed.
- These findings support the interpretation of the MMT trial results based on its program theory.
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