Evidence of Cardiac Rehabilitation for Heart Failure With Reduced Ejection Fraction in Recovery to Maintenance Phase

Naoto Miyawaki1, Akira Takashima2

  • 1Department of Rehabilitation, Kitajima Taoka Hospital Tokushima Japan.

Circulation Reports
|January 13, 2025
PubMed

Insights

Cardiac rehabilitation (CR) improves exercise capacity and quality of life for patients with heart failure (HF) with reduced left ventricular ejection fraction (HFrEF). Long-term CR may also reduce mortality, with future research focusing on updated, technology-assisted programs.

Area of Science:

  • Cardiology
  • Rehabilitation Medicine

Background:

  • Heart failure (HF) with reduced left ventricular ejection fraction (HFrEF) involves cardiac remodeling and requires comprehensive management.
  • Pharmacologic therapy is primary, but cardiac rehabilitation (CR) is strongly recommended for HFrEF patients.

Purpose of the Study:

  • To review the accumulating evidence on the benefits of CR for HFrEF.
  • To discuss the future directions for CR in HFrEF, considering technological advancements and an aging population.

Main Methods:

  • Systematic review of existing literature on CR for HFrEF.
  • Analysis of CR's impact on exercise tolerance, symptoms, quality of life, rehospitalization, and mortality.

Main Results:

  • CR significantly improves exercise tolerance, HF symptoms, and quality of life.
  • CR reduces rehospitalization rates and may improve all-cause mortality, particularly in the long term.
  • Evidence suggests CR benefits are sustained and potentially enhanced over time.

Conclusions:

  • CR is a vital component of HFrEF management, offering significant benefits beyond pharmacologic treatment.
  • Future CR programs for HFrEF should integrate technology and be adaptable for home-based or remote settings, especially for older adults.
  • Further research is needed to optimize exercise protocols and delivery methods for evolving CR interventions.

Related Concept Videos

Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.5K
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
381
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
722