The Impact of Air Pollution on Acute Angle-Closure Glaucoma in Hefei, China, 2017-2022: A Time-Series Study
Si-Tian Zhang1, Li-Qing Wang, Yan-Cheng Fang
1From the Department of Ophthalmology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China (S.-T.Z., L.-Q.W., Y.-C.F., Y.-F.Z.); Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China (W.-B.S., F.H.); Department of Ophthalmology, the First People's Hospital of Hefei, Hefei, Anhui, China (Y.-L.L.); Department of Ophthalmology, the First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui, China (B.S.); Department of Ophthalmology, the Second People's Hospital of Hefei, Hefei, Anhui, China (Y.-R.L.); Department of Ophthalmology, Anhui No.2 Provincial People's Hospital, Hefei, Anhui, China (X.-H.H.); and Department of Ophthalmology, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China (H.-T.L.).
Objective:
The study investigated the effects of air pollutants on the incidence of acute angle-closure glaucoma (AACG) in Hefei, China.
Methods:
A combination of generalized additive models and distributed lag nonlinear models was used to explore the relationship between air pollutants and the incidence of AACG.
Results:
Exposure-response curves showed that exposure to PM 2.5 , PM 10 , NO 2 , SO 2 , CO, and O 3 were all positively correlated with the onset of AACG. Among them, NO 2 , and CO having higher relative risk values for AACG onset.
Conclusions:
This study highlighted the potential risks of these pollutants and expanded the knowledge of the environmental role in AACG incidence, which will encourage local governments to adopt policy measures and guidance to improve public health.
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