Related Experiment Video
Updated: Jul 28, 2026
A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
Published on: November 3, 2016
Hand function in children with myelomeningocele
Insights
Myelomeningocele significantly impacts hand function in children, with 85% experiencing cerebellar ataxia. Early intervention and practice can improve dexterity and coordination in affected individuals.
Area of Science:
- Pediatric Neurology
- Rehabilitation Medicine
- Developmental Neuroscience
Background:
- Myelomeningocele is a complex congenital condition affecting neurological development.
- Impaired hand function is a common challenge for children with myelomeningocele, impacting daily activities.
- Understanding factors influencing hand function is crucial for targeted interventions.
Purpose of the Study:
- To assess hand function in children with myelomeningocele.
- To identify factors associated with better or poorer hand function.
- To explore potential strategies for improving hand function in this population.
Main Methods:
- Clinical examination of hand function in 33 patients (aged 4-17 years).
- Formal testing of upper limb coordination and manual dexterity.
- Analysis of correlations between hand function and clinical variables (e.g., hydrocephalus severity, lesion level).
Main Results:
- Average hand function was 59% of normal; only two patients had normal upper limbs.
- Cerebellar ataxia was present in 85% of patients, often with upper motor neuron lesions.
- Hand function improved with age (≥11 years), milder hydrocephalus, and in younger right-handed children.
Conclusions:
- Hand function deficits are prevalent in myelomeningocele, with cerebellar ataxia being a common comorbidity.
- Age, hydrocephalus severity, and handedness are significant factors influencing hand function.
- Early rehabilitation focusing on posture and skillful hand use may enhance functional outcomes.
Abstract:
Hand function in 33 patients with myelomeningocele, aged from 4 to 17 years, was investigated by clinical examination and formal tests of co-ordination and dexterity. The average score for hand function was 59% of normal and only two children had clinically normal upper limbs. Twenty-eight patients (85%) had cerebellar ataxia, either alone or combined with other abnormal signs, most commonly upper motor neuron lesions. Hand function was significantly better in children of 11 years and older, in children under 11 with milder degrees of hydrocephalus, and in the younger children who were right-handed. Function was not shown to be better in those with lesions lower in the spine, nor in those with stable spines as has been previously reported. When co-ordination of the upper limb, manual dexterity and simultaneous movements of both arms were examined separately, these three were affected equally. Some abnormalities of hand function could be overcome by encouraging affected children to sit up and to practise skillful use of their hands as early in life as possible.
