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Related Experiment Video

Updated: Jul 28, 2026

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
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Hand function in children with myelomeningocele.

A Turner

    The Journal of Bone and Joint Surgery. British Volume
    |March 1, 1985
    PubMed
    Summary

    Myelomeningocele significantly impacts hand function in children, with 85% experiencing cerebellar ataxia. Early intervention and practice can improve dexterity and coordination in affected individuals.

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    Area of Science:

    • Pediatric Neurology
    • Rehabilitation Medicine
    • Developmental Neuroscience

    Background:

    • Myelomeningocele is a complex congenital condition affecting neurological development.
    • Impaired hand function is a common challenge for children with myelomeningocele, impacting daily activities.
    • Understanding factors influencing hand function is crucial for targeted interventions.

    Purpose of the Study:

    • To assess hand function in children with myelomeningocele.
    • To identify factors associated with better or poorer hand function.
    • To explore potential strategies for improving hand function in this population.

    Main Methods:

    • Clinical examination of hand function in 33 patients (aged 4-17 years).
    • Formal testing of upper limb coordination and manual dexterity.
    • Analysis of correlations between hand function and clinical variables (e.g., hydrocephalus severity, lesion level).

    Main Results:

    • Average hand function was 59% of normal; only two patients had normal upper limbs.
    • Cerebellar ataxia was present in 85% of patients, often with upper motor neuron lesions.
    • Hand function improved with age (≥11 years), milder hydrocephalus, and in younger right-handed children.

    Conclusions:

    • Hand function deficits are prevalent in myelomeningocele, with cerebellar ataxia being a common comorbidity.
    • Age, hydrocephalus severity, and handedness are significant factors influencing hand function.
    • Early rehabilitation focusing on posture and skillful hand use may enhance functional outcomes.

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