Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...

Mass Spectrometry: Branched Alkane Fragmentation

Mass Spectrometry: Branched Alkane Fragmentation

This lesson delves into the mass spectrometry of branched alkane fragmentation. Branched alkanes possess secondary or tertiary carbon atoms, which generate relatively stable carbocations if the cleavage occurs at the branching point. The high stability of carbocations drives the instant fragmentation of branched alkanes. Accordingly, the branched alkane's molecular ion peak is very weak or invisible in the mass spectra, especially in comparison to a linear alkane.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Lonicerin alleviates the progression of experimental rheumatoid arthritis by downregulating M1 macrophages through the NF-κB signaling pathway.

Phytotherapy research : PTR·2023

Same author

Evolution-guided multiomics provide insights into the strengthening of bioactive flavone biosynthesis in medicinal pummelo.

Plant biotechnology journal·2023

Same author

Photosynthetic Fixation of CO<sub>2</sub> in Alkenes by Heterogeneous Photoredox Catalysis with Visible Light.

Angewandte Chemie (International ed. in English)·2023

Same author

In Situ Trapping Strategy Enables a High-Loading Ni Single-Atom Catalyst as a Separator Modifier for a High-Performance Li-S Battery.

ACS applied materials & interfaces·2023

Same author

A novel thin single-phase drive linear ultrasonic motor.

The Review of scientific instruments·2023

Same author

Celastrol inhibits necroptosis by attenuating the RIPK1/RIPK3/MLKL pathway and confers protection against acute pancreatitis in mice.

International immunopharmacology·2023

Same journal

[TCM understanding and classical formula treatment strategies for type 2 diabetes mellitus].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·2026

Same journal

[Assessment of therapeutic effectiveness and underlying pharmacological mechanisms of Tripterygium glycosides for systemic lupus erythematosus: umbrella review and in silico study].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·2026

Same journal

[Psoralen attenuates skeletal muscle atrophy in mice with heart failure after myocardial infarction by regulating NLRP3/Caspase-1/GSDMD pathway].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·2026

Same journal

[Shared mechanisms of obesity and male infertility and prediction of natural therapeutics based on machine learning and single-cell sequencing].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·2026

Same journal

[Mechanism study on treating psoriasis of blood-heat type with Tuhuaidan Siwu Decoction based on metabolomics and p38 MAPK/NF-κB signaling pathway].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·2026

Same journal

[Regulatory effects of serum containing Hedysari Radix Praeparata Cum Melle-vinegar processed Curcumae Rhizoma on mitochondrial function and mitophagy in HT-29 cells].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 2, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

[A new nortriterpenoid from mastic].

Xue-Rui An¹, Ya-Ping Feng¹, Yu-Wei Sun¹

¹Xinjiang Key Laboratory of Clean Conversion and High Value Utilization of Biomass Resources,School of Chemistry and Chemical Engineering, Yili Normal University Yining 835000, China.

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica

|January 13, 2025

Summary

This summary is machine-generated.

Mastic compounds show potent anti-inflammatory and anti-cancer effects. A novel compound, 17β-hydroxy-28-norolean-18-en-3-one, significantly inhibited nitric oxide production in macrophages.

Keywords:

anti-colorectal cancer anti-inflammatory chemical constituents mastic nortriterpenoid

More Related Videos

Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale

Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale

Published on: August 16, 2018

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques

Published on: March 8, 2024

Related Experiment Videos

Last Updated: Jun 2, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale

Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale

Published on: August 16, 2018

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques

Published on: March 8, 2024

Area of Science:

Phytochemistry
Natural Products Chemistry
Pharmacology

Context:

Mastic, a resin from Pistacia lentiscus, is traditionally used for medicinal purposes.
Modern chromatographic techniques enable the isolation and identification of complex natural products.
Understanding the bioactivity of mastic constituents is crucial for potential therapeutic applications.

Purpose:

To isolate and characterize compounds from mastic using advanced analytical methods.
To evaluate the anti-inflammatory and anti-proliferative activities of the isolated compounds.
To identify novel compounds and natural products from mastic.

Summary:

Ten compounds were isolated from mastic, including a novel compound (1) and a novel natural product (2).
Compounds 1-2, 4, and 7-9 were reported from mastic for the first time.
Compound 1 demonstrated significant inhibition of nitric oxide production in RAW264.7 cells, outperforming dexamethasone.
Several other compounds exhibited notable anti-inflammatory and anti-proliferative effects against colon cancer cells (SW480).

Impact:

Identifies a novel compound with potent anti-inflammatory properties.
Provides evidence for the anti-cancer potential of mastic-derived compounds.
Expands the knowledge of mastic phytochemistry and its biological activities.