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Examining homology between MPXV and immunogenic VACV-derived peptides.

Lara I Teodoro1, Inna G Ovsyannikova1, Gregory A Poland1

  • 1Mayo Clinic Vaccine Research Group, Mayo Clinic, Rochester, MN 55905, USA.

Vaccine
|January 14, 2025
PubMed
Summary

Current mpox vaccines use whole vaccinia viruses. This study found high sequence homology between vaccinia-derived peptides and mpox virus, suggesting potential for new, stable peptide-based mpox vaccines.

Keywords:
CladeDiseaseEpitopeHomologyMPXVMonkeypoxMpoxMpox vaccinePeptide-based vaccineSequence

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