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Updated: Jun 14, 2025

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
Published on: December 27, 2024
Primary spinal conus medullaris germinoma
Yang Chen1, Chia-Wen Li2, Wei-Lung Tseng3
1Surgery, Fu Jen Catholic University Hospital, New Taipei City, Taiwan.
Abstract:
A woman in her early 20s presented with progressive low back pain, leg weakness and sphincter dysfunction. MRI revealed a 5 × 1.5 cm intramedullary tumour at the T12-L2 level. Elevated preoperative beta-human chorionic gonadotropin levels were noted. Surgical excision confirmed the diagnosis of a germinoma. Postoperative MRI showed no additional lesions. The patient underwent localized radiation therapy, but recurrence was noted 10 months later.
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