Mycotic Aneurysm in Salmonella enteritidis Infection: A Fatal Complication

Grace Gui Jin Khoo1, Paul Andrew Chong Yew Ong1, Joel Kae Wei Wong1

  • 1Internal Medicine, Hospital Sultanah Aminah, Johor Bahru, MYS.

Cureus
|January 15, 2025
PubMed

Insights

Salmonella enteritidis can cause rare but deadly mycotic aneurysms. Early detection and treatment are crucial for high-risk patients to prevent fatal rupture.

Area of Science:

  • Infectious Diseases
  • Vascular Surgery
  • Cardiology

Background:

  • Mycotic aneurysms are rare, severe infections of blood vessels, often fatal.
  • Systemic bacterial infections, like Salmonella bacteremia, are primary causes.
  • Diabetes mellitus increases risk for severe infections and complications.

Observation:

  • A 62-year-old male with type 2 diabetes presented in septic shock.
  • Blood cultures confirmed Salmonella enteritidis bacteremia.
  • CT angiogram revealed a ruptured infrarenal abdominal aortic mycotic aneurysm.

Findings:

  • Despite aggressive treatment, the patient experienced rapid deterioration.
  • Death was attributed to the ruptured mycotic aneurysm.
  • Salmonella enteritidis bacteremia was the likely cause of the aneurysm.

Implications:

  • Vigilance for mycotic aneurysms is critical in Salmonella bacteremia patients.
  • Elderly patients and those with cardiovascular disease are at higher risk.
  • Prompt diagnosis via imaging and timely intervention are essential to improve survival rates and prevent mortality.

Related Concept Videos

Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
89
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
88
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
15