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Published on: September 22, 2019
Mycotic Aneurysm in Salmonella enteritidis Infection: A Fatal Complication
Grace Gui Jin Khoo1, Paul Andrew Chong Yew Ong1, Joel Kae Wei Wong1
1Internal Medicine, Hospital Sultanah Aminah, Johor Bahru, MYS.
Abstract:
Mycotic aneurysms are rare but severe complications that can arise from systemic bacterial infections, including those caused by Salmonella species. These aneurysms can progress rapidly and are associated with high mortality. A 62-year-old man with poorly controlled type 2 diabetes mellitus presented to the hospital in septic shock. The blood culture grew Salmonella enteritidis. A computed tomography angiogram showed a ruptured mycotic aneurysm of the infrarenal abdominal aorta. Despite antibiotic therapy and supportive care, the patient's condition rapidly deteriorated, resulting in his death, most likely due to aneurysm rupture. This case highlights the importance of vigilance in patients with Salmonella bacteremia, particularly in high-risk individuals, such as the elderly and people with underlying cardiovascular diseases. Early imaging and timely intervention are critical for improving outcomes and preventing fatal complications, such as aneurysm rupture.
Insights
Salmonella enteritidis can cause rare but deadly mycotic aneurysms. Early detection and treatment are crucial for high-risk patients to prevent fatal rupture.
Area of Science:
- Infectious Diseases
- Vascular Surgery
- Cardiology
Background:
- Mycotic aneurysms are rare, severe infections of blood vessels, often fatal.
- Systemic bacterial infections, like Salmonella bacteremia, are primary causes.
- Diabetes mellitus increases risk for severe infections and complications.
Observation:
- A 62-year-old male with type 2 diabetes presented in septic shock.
- Blood cultures confirmed Salmonella enteritidis bacteremia.
- CT angiogram revealed a ruptured infrarenal abdominal aortic mycotic aneurysm.
Findings:
- Despite aggressive treatment, the patient experienced rapid deterioration.
- Death was attributed to the ruptured mycotic aneurysm.
- Salmonella enteritidis bacteremia was the likely cause of the aneurysm.
Implications:
- Vigilance for mycotic aneurysms is critical in Salmonella bacteremia patients.
- Elderly patients and those with cardiovascular disease are at higher risk.
- Prompt diagnosis via imaging and timely intervention are essential to improve survival rates and prevent mortality.
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