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Updated: Jun 2, 2025

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry UPLC-MS

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry UPLC-MS

Published on: March 14, 2013

Metabolic Profiling: A Perspective on the Current Status, Challenges, and Future Directions.

Helen G Gika^1,2, Georgios Theodoridis^2,3,4, Ian D Wilson⁵

¹Department of Medicine, Aristotle University, Thessaloniki, Greece.

Methods in Molecular Biology (Clifton, N.J.)

|January 15, 2025

Summary

This summary is machine-generated.

Metabolic phenotyping, also known as metabolomics, is a globally researched field. This perspective reviews its current status, challenges, and future directions in biomarker and systems biology research.

Keywords:

Biomarker discovery Metabolic markers Metabolic phenotyping Metabolic profiling Metabolomics Metabonomics

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Published on: May 20, 2013

Area of Science:

Biomarker Research
Systems Biology
Metabolomics

Background:

Metabolic profiling is a rapidly advancing scientific field.
Research is conducted globally across various laboratory scales.
It plays a crucial role in understanding biological systems.

Purpose of the Study:

To provide a perspective on the current status of metabolic phenotyping.
To identify key challenges in the field of metabolomics.
To consider future research directions for metabolic profiling.

Main Methods:

Literature review and expert perspective.
Analysis of global research trends in metabolic phenotyping.
Discussion of current technological and analytical challenges.

Main Results:

Metabolic phenotyping is a widespread and growing area of research.
Significant challenges exist in data analysis, standardization, and interpretation.
The field holds immense potential for biomarker discovery and systems biology.

Conclusions:

Metabolic phenotyping is a vital and evolving discipline.
Addressing current challenges is crucial for future advancements.
Continued research will enhance its application in health and disease.